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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LPP All Species: 15.45
Human Site: Y273 Identified Species: 28.33
UniProt: Q93052 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93052 NP_005569.1 612 65746 Y273 S T R G G M D Y A Y I P P P G
Chimpanzee Pan troglodytes XP_001159584 680 73450 Y341 S T R G G M D Y A Y I P P P G
Rhesus Macaque Macaca mulatta XP_001104284 416 44041 G86 S A L P S I S G N F P P P P P
Dog Lupus familis XP_850342 615 65837 Y276 S T R G G M D Y A Y M P P P G
Cat Felis silvestris
Mouse Mus musculus Q8BFW7 613 65872 Y274 P T C V G T D Y A Y I P P S G
Rat Rattus norvegicus Q5XI07 632 68242 Y270 T T C A G T D Y A Y I P P S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512190 613 66056 G274 A P S Q P R G G P D Y G Y T P
Chicken Gallus gallus Q5F464 604 65121 G265 P P G A Q Q Y G S P Q P R G P
Frog Xenopus laevis A5H447 663 70707 P325 A A K H E A P P P T V P S G G
Zebra Danio Brachydanio rerio A8DZE6 648 70883 Q296 P R S S I C S Q P A V A A N C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396072 477 52619 P147 H N N D D L P P P P E P S E Y
Nematode Worm Caenorhab. elegans Q09476 413 46434 K82 S E G K D Y S K S Q E R I Y E
Sea Urchin Strong. purpuratus XP_798292 448 48550 P118 L S N A R G L P S Y S P V D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.8 66.5 92.5 N.A. 89.4 83.8 N.A. 81.4 78.7 31.8 27 N.A. N.A. 34.6 22 38.2
Protein Similarity: 100 89.8 66.8 93.9 N.A. 92 87.8 N.A. 84 82.6 45.8 41.6 N.A. N.A. 49.8 35.2 46.9
P-Site Identity: 100 100 26.6 93.3 N.A. 66.6 66.6 N.A. 0 6.6 13.3 0 N.A. N.A. 6.6 6.6 13.3
P-Site Similarity: 100 100 40 100 N.A. 66.6 73.3 N.A. 6.6 13.3 33.3 6.6 N.A. N.A. 13.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 16 0 24 0 8 0 0 39 8 0 8 8 0 0 % A
% Cys: 0 0 16 0 0 8 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 8 16 0 39 0 0 8 0 0 0 8 0 % D
% Glu: 0 8 0 0 8 0 0 0 0 0 16 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 16 24 39 8 8 24 0 0 0 8 0 16 47 % G
% His: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 8 0 0 0 0 31 0 8 0 0 % I
% Lys: 0 0 8 8 0 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 8 0 8 0 0 8 8 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 24 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 16 0 0 0 0 0 8 0 0 0 0 8 0 % N
% Pro: 24 16 0 8 8 0 16 24 31 16 8 77 47 31 24 % P
% Gln: 0 0 0 8 8 8 0 8 0 8 8 0 0 0 0 % Q
% Arg: 0 8 24 0 8 8 0 0 0 0 0 8 8 0 0 % R
% Ser: 39 8 16 8 8 0 24 0 24 0 8 0 16 16 0 % S
% Thr: 8 39 0 0 0 16 0 0 0 8 0 0 0 8 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 16 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 8 39 0 47 8 0 8 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _